High hierarchy

B-cell lineage

Low hierarchy

Pre-pro-B cells

Description

the earliest primitive B cell progenitors which express CD34 and SPINK2, have germline Ig genes and give rise to Pro-B cells

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Curated Markers

Top Model Markers

Datasets

Suo et al. 2022
PubMed

Tissues

  • Bone marrow
  • Gut
  • Kidney
  • Liver
  • Lymph node
  • Skin
  • Spleen
  • Thymus
  • Yolk sac

Ontology CL:0002046

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